Avshalom Caspi

Edward M. Arnett Professor of Psychology and Neuroscience in Trinity College of Arts and Sciences

Education & Training

  • Ph.D., Cornell University 1986

  • M.A., Cornell University 1983

  • B.A., University of California at Santa Cruz 1981


Development, epidemiology, genetics, health inequalities, personality

Baldwin, JR, Arseneault, L, Caspi, A, Fisher, HL, Moffitt, TE, Odgers, CL, Pariante, C, Ambler, A, Dove, R, Kepa, A, Matthews, T, Menard, A, Sugden, K, Williams, B, and Danese, A. "Childhood victimization and inflammation in young adulthood: A genetically sensitive cohort study. (Accepted)" Brain, behavior, and immunity 67 (January 2018): 211-217. Full Text

Newbury, JB, Arseneault, L, Moffitt, TE, Caspi, A, Danese, A, Baldwin, JR, and Fisher, HL. "Measuring childhood maltreatment to predict early-adult psychopathology: Comparison of prospective informant-reports and retrospective self-reports." Journal of psychiatric research 96 (September 21, 2017): 57-64. Full Text

Suppli, NP, Bukh, JD, Moffitt, TE, Caspi, A, Johansen, C, Tjønneland, A, Kessing, LV, and Dalton, SO. "Genetic variants in 5-HTTLPR, BDNF, HTR1A, COMT, and FKBP5 and risk for treated depression after cancer diagnosis." Depression and anxiety 34.9 (September 2017): 845-855. Full Text

Matthews, T, Danese, A, Gregory, AM, Caspi, A, Moffitt, TE, and Arseneault, L. "Sleeping with one eye open: loneliness and sleep quality in young adults." Psychological Medicine 47.12 (September 2017): 2177-2186. Full Text

Williams, MJA, Milne, BJ, Ambler, A, Theodore, R, Ramrakha, S, Caspi, A, Moffitt, TE, and Poulton, R. "Childhood body mass index and endothelial dysfunction evaluated by peripheral arterial tonometry in early midlife." International Journal of Obesity (2005) 41.9 (September 2017): 1355-1360. Full Text

Belsky, DW, Caspi, A, Cohen, HJ, Kraus, WE, Ramrakha, S, Poulton, R, and Moffitt, TE. "Impact of early personal-history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan." Aging cell 16.4 (August 2017): 644-651. Full Text

Meier, MH, Caspi, A, Danese, A, Fisher, HL, Houts, R, Arseneault, L, and Moffitt, TE. "Associations between adolescent cannabis use and neuropsychological decline: a longitudinal co-twin control study." Addiction (Abingdon, England) (July 22, 2017). Full Text

Kotov, R, Krueger, RF, Watson, D, Achenbach, TM, Althoff, RR, Bagby, RM, Brown, TA, Carpenter, WT, Caspi, A, Clark, LA, Eaton, NR, Forbes, MK, Forbush, KT, Goldberg, D, Hasin, D, Hyman, SE, Ivanova, MY, Lynam, DR, Markon, K, Miller, JD, Moffitt, TE, Morey, LC, Mullins-Sweatt, SN, Ormel, J, Patrick, CJ, Regier, DA, Rescorla, L, Ruggero, CJ, Samuel, DB, Sellbom, M, Simms, LJ, Skodol, AE, Slade, T, South, SC, Tackett, JL, Waldman, ID, Waszczuk, MA, Widiger, TA, Wright, AGC, and Zimmerman, M. "The Hierarchical Taxonomy of Psychopathology (HiTOP): A dimensional alternative to traditional nosologies." Journal of abnormal psychology 126.4 (May 2017): 454-477. Full Text

Romer, AL, Knodt, AR, Houts, R, Brigidi, BD, Moffitt, TE, Caspi, A, and Hariri, AR. "Structural alterations within cerebellar circuitry are associated with general liability for common mental disorders." Molecular psychiatry (April 11, 2017). Full Text

Danese, A, Moffitt, TE, Arseneault, L, Bleiberg, BA, Dinardo, PB, Gandelman, SB, Houts, R, Ambler, A, Fisher, HL, Poulton, R, and Caspi, A. "The Origins of Cognitive Deficits in Victimized Children: Implications for Neuroscientists and Clinicians." The American journal of psychiatry 174.4 (April 2017): 349-361. Full Text


Fisher, H, Caspi, A, Moffitt, T, York-Smith, M, Newbury, J, Uher, R, and Arseneault, L. "Poly-victimisation and Adolescent Psychotic Symptoms in a Nationally-Representative Prospective Cohort Study of Twins." October 2016.

Newbury, J, Arseneault, L, Caspi, A, Moffitt, TE, Odgers, CL, and Fisher, HL. "Neighbourhood Adversity, Crime Victimisation and Adolescent Psychotic Experiences: Findings from a Longitudinal Cohort Study." October 2016.

Fisher, H, Caspi, A, Shalev, I, Meier, M, Houts, R, Harrington, H, Poulton, R, and Moffitt, T. "Accelerated biological aging in schizophrenia." November 2014.

Fisher, H, Murphy, T, Arseneault, L, Burrage, J, Dempster, E, Caspi, A, Moffitt, T, and Mill, J. "Genome-wide DNA methylation profiling in monozygotic twins discordant for psychotic symptoms at age 12." November 2014.

Reichenberg, A, Caspi, A, Harrington, H, Houts, R, Keefe, RS, Murray, RM, Poulton, R, and Moffitt, TE. "Static and Dynamic Cognitive Deficits in Childhood Precede Adult Schizophrenia: A 30-Year Study." May 1, 2010.

Reichenberg, A, Caspi, A, Harrington, H, Houts, R, Keefe, R, Murray, R, Poulton, R, and Moffitt, T. "STATIC AND DYNAMIC COGNITIVE DEFICITS IN CHILDHOOD PRECEDE ADULT SCHIZOPHRENIA: A 30-YEAR STUDY." April 2010. Full Text

Selected Grants

Summer Scholars Program in Genome Sciences and Medicine awarded by National Institutes of Health (Significant Contributor). 2017 to 2022

Behavioral and Physiology in Aging awarded by National Institutes of Health (Mentor). 2015 to 2020

Aging in 1000 healthy young adults: the Dunedin Study awarded by National Institutes of Health (Co-Principal Investigator). 2009 to 2020

Neural signatures of healthy and unhealthy aging awarded by National Institutes of Health (Investigator). 2015 to 2020

Neuropsychological and genomic signatures of violence exposure in childhood awarded by National Institutes of Health (Principal Investigator). 2013 to 2018

Generating new knowledge to support reversibility interventions awarded by National Institutes of Health (Co Investigator). 2014 to 2017

Genetic and Behavioral Predictors of Susceptibility to Social Stress awarded by National Science Foundation (Co-Principal Investigator). 2013 to 2015

Behavior And Physiology In Aging awarded by National Institutes of Health (Mentor). 1999 to 2015

Social Inequality and Children's Mental Health awarded by National Institutes of Health (Principal Investigator). 2009 to 2014

A developmental model of gene-environment interplay in SUDs awarded by National Institutes of Health (Consultant). 2007 to 2014