Christina S. Meade

Christina S. Meade

Associate Professor in Psychiatry and Behavioral Sciences

Education & Training

  • Ph.D., Yale University 2006

Overview

Dr. Meade’s domestic research program focuses on predictors of HIV risk behavior in adults with substance use and psychiatric disorders, and the relationship between neuropsychiatric conditions and continued risk behavior in HIV-positive adults. She is particularly interested in how drug addiction and HIV infection impact executive functions, such as decision making, that lead individuals to engage in risky behaviors. Many of her current projects incorporate MRI to isolate the effects of addiction and HIV on both brain function and structure. Dr. Meade is also interested in the development of evidence-based treatments to improve cognitive functioning and reduce risk behaviors among drug users.

Given that most people infected or affected by HIV/AIDS live in Sub-Saharan Africa, Dr. Meade’s international research program is based in South Africa. The Western Cape has experienced a dramatic increase in methamphetamine use since the early 2000s, and there is concern that it may further fuel the HIV epidemic in this country. Current projects focus on characterizing drug addiction and HIV risk behaviors in this understudied group, both in in community and treatment settings, and ultimately increasing uptake of HIV services to improve health outcomes and reduce the continued spread of HIV.

Towe, SL, Horton, OE, Martin, B, and Meade, CS. "A Comparison of Motivations for Marijuana Use in HIV-Positive and HIV-Negative Adults." Aids and Behavior 22.9 (September 2018): 2807-2814. Full Text

Bell, RP, Barnes, LL, Towe, SL, Chen, N-K, Song, AW, and Meade, CS. "Structural connectome differences in HIV infection: brain network segregation associated with nadir CD4 cell count." Journal of Neurovirology 24.4 (August 2018): 454-463. Full Text

Khatiwoda, P, Proeschold-Bell, RJ, Meade, CS, Park, LP, and Proescholdbell, S. "Facilitators and Barriers to Naloxone Kit Use Among Opioid-Dependent Patients Enrolled in Medication Assisted Therapy Clinics in North Carolina." North Carolina Medical Journal 79.3 (May 2018): 149-155. Full Text

Meade, CS, Addicott, M, Hobkirk, AL, Towe, SL, Chen, N-K, Sridharan, S, and Huettel, SA. "Cocaine and HIV are independently associated with neural activation in response to gain and loss valuation during economic risky choice." Addiction biology 23.2 (March 2018): 796-809. Full Text

Skalski, LM, Towe, SL, Sikkema, KJ, and Meade, CS. "Memory Impairment in HIV-Infected Individuals with Early and Late Initiation of Regular Marijuana Use." AIDS and behavior (September 7, 2017). Full Text

Meade, CS, Hobkirk, AL, Towe, SL, Chen, N-K, Bell, RP, and Huettel, SA. "Cocaine dependence modulates the effect of HIV infection on brain activation during intertemporal decision making." Drug and Alcohol Dependence 178 (September 2017): 443-451. Full Text

Towe, SL, Patel, P, and Meade, CS. "The Acceptability and Potential Utility of Cognitive Training to Improve Working Memory in Persons Living With HIV: A Preliminary Randomized Trial." The Journal of the Association of Nurses in AIDS Care : JANAC 28.4 (July 2017): 633-643. Full Text

Berg, MK, Hobkirk, AL, Joska, JA, and Meade, CS. "The role of substance use coping in the relation between childhood sexual abuse and depression among methamphetamine users in South Africa." Psychological trauma : theory, research, practice and policy 9.4 (July 2017): 493-499. Full Text

Cordero, DM, Towe, SL, Chen, N-K, Robertson, KR, Madden, DJ, Huettel, SA, and Meade, CS. "Cocaine dependence does not contribute substantially to white matter abnormalities in HIV infection." Journal of neurovirology 23.3 (June 2017): 441-450. Full Text

Lion, RR, Watt, MH, Wechsberg, WM, and Meade, CS. "Gender and Sex Trading Among Active Methamphetamine Users in Cape Town, South Africa." Substance Use & Misuse 52.6 (May 2017): 773-784. Full Text

Pages

Miles, MS, Holditch-Davis, D, Pedersen, C, J Eron, J, Schwartz, T, Sikkema, KJ, Meade, CS, Doughty-Berry, JD, Zimmerman, SO, Kloos, B, and Snow, DL. "Emotional distress in african american women with hivCommunity-level hiv prevention for persons with severe mental illness living in supportive housing programs: A pilot intervention study (PublishedPublished)." HIV: Issues with Mental Health and Illness. January 1, 2014. 35-50. Full Text

Sikkema, KJ, Meade, CS, Doughty Berry, JD, Zimmerman, SO, Kloos, B, and Snow, DL. "Community-level HIV prevention for persons with severe mental illness living in supportive housing programs: a pilot intervention study." HIV: Issues with Mental Health and Illness. Ed. MM Eisenberg and MB Blank. The Hawthorne Press, Inc., 2007. 121-135. (Essay) Full Text

Selected Grants

Role of cannabis on HIV-related cognitive impairment: a brain connectomics study awarded by National Institutes of Health (Principal Investigator). 2018 to 2023

MRI data fusion to investigate effects of drug abuse on HIV neurological complications awarded by National Institutes of Health (Principal Investigator). 2018 to 2023

Mobile health interventions for varenicline adherence among HIV-positive smokers awarded by National Institutes of Health (Co-Mentor). 2017 to 2022

A Systems Biology Approach to HIV-associated Neurocognitive Impairment: Role of Drug Abuse and Neuroinflammation awarded by National Institutes of Health (Co-Principal Investigator). 2016 to 2021

Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health (Mentor). 2010 to 2020

Decision Making and HIV Risk: New Approaches to neuroAIDS Research in Drug Users awarded by National Institutes of Health (Principal Investigator). 2015 to 2020

Cognitive Training to Reduce Impulsivity in HIV-infected Cocaine Users awarded by National Institutes of Health (Principal Investigator). 2016 to 2019

NeuroAIDS research with disadvantaged drug users awarded by National Institutes of Health (Principal Investigator). 2014 to 2017

A Compute Cluster for Brain Imaging and Analysis awarded by National Institutes of Health (Minor User). 2016 to 2017

Effects of Cocaine and HIV Decision Making Involving Potential Loss awarded by National Institutes of Health (Principal Investigator). 2013 to 2016

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