Daniel W Belsky

Assistant Professor in Population Health Sciences

Education & Training

  • Ph.D., University of North Carolina at Chapel Hill 2012

Overview

The goal of Dan’s work is to reduce social inequalities in aging outcomes in the US and elsewhere. Dan's research seeks to understand how genes and environments combine to shape health across the life course. His work uses tools from genome science and longitudinal data from population-based cohort studies. The aim is to identify targets for policy and clinical interventions to promote positive development in early life and extend healthspan.

Areas of interest: Aging, health disparities, epidemiology, life course, genetics, genomics, gene-environment interaction, health measurement

After finishing his Ph.D. at the UNC Gillings School of Public Health in 2012, Dan came to Duke for a postdoc at the Center for The Study of Aging and Human Development. Dan joined the faculty at Duke in 2014. He is Assistant Professor in the Department of Medicine, Division of Geriatrics at the Duke University School of Medicine and Social Science Research Institute. Dan is a Senior Fellow at the Aging Center and a Research Scholar at the Duke Population Research Institute.

Areas of expertise: Epidemiology and Health Measurement

Domingue, BW, Liu, H, Okbay, A, and Belsky, DW. "Genetic Heterogeneity in Depressive Symptoms Following the Death of a Spouse: Polygenic Score Analysis of the U.S. Health and Retirement Study." The American journal of psychiatry 174.10 (October 2017): 963-970. Full Text

Domingue, BW, Belsky, DW, Harrati, A, Conley, D, Weir, DR, and Boardman, JD. "Mortality selection in a genetic sample and implications for association studies." International Journal of Epidemiology 46.4 (August 1, 2017): 1285-1294. Full Text Open Access Copy

Belsky, DW, Caspi, A, Cohen, HJ, Kraus, WE, Ramrakha, S, Poulton, R, and Moffitt, TE. "Impact of early personal-history characteristics on the Pace of Aging: implications for clinical trials of therapies to slow aging and extend healthspan." Aging cell 16.4 (August 2017): 644-651. Full Text

Belsky, DW. "Translating Polygenic Analysis for Prevention." Circulation: Cardiovascular Genetics 10.3 (June 2017): e001798-e001798. Full Text Open Access Copy

Belsky, DW, Huffman, KM, Pieper, CF, Shalev, I, and Kraus, WE. "Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis." The journals of gerontology. Series A, Biological sciences and medical sciences (May 22, 2017). Full Text Open Access Copy

Domingue, BW, and Belsky, DW. "The social genome: Current findings and implications for the study of human genetics." PLoS genetics 13.3 (March 16, 2017): e1006615-. Full Text

Reuben, A, Caspi, A, Belsky, DW, Broadbent, J, Harrington, H, Sugden, K, Houts, RM, Ramrakha, S, Poulton, R, and Moffitt, TE. "Association of Childhood Blood Lead Levels With Cognitive Function and Socioeconomic Status at Age 38 Years and With IQ Change and Socioeconomic Mobility Between Childhood and Adulthood." JAMA 317.12 (March 2017): 1244-1251. Full Text

Moffitt, TE, Belsky, DW, Danese, A, Poulton, R, and Caspi, A. "The Longitudinal Study of Aging in Human Young Adults: Knowledge Gaps and Research Agenda." The journals of gerontology. Series A, Biological sciences and medical sciences 72.2 (February 2017): 210-215. Full Text

Pages

Selected Grants

A pilot study to advance translation of molecular signatures of biological aging awarded by National Institutes of Health (Principal Investigator). 2017 to 2029

Aging in 1000 healthy young adults: the Dunedin Study awarded by National Institutes of Health (Co Investigator). 2009 to 2020

Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative awarded by National Institutes of Health (Investigator). 2017 to 2019

Early Career Research Fellowship awarded by Jacobs Foundation (Principal Investigator). 2016 to 2018

Investigating increasing selectivity of low educational attainment across US birth cohorts in the 20th Century awarded by National Institutes of Health (Principal Investigator). 2016 to 2018

Generating new knowledge to support reversibility interventions awarded by National Institutes of Health (Co Investigator). 2014 to 2017

Subcontract - The Social and Genetic Epidemiology of Health Behaviors: An Integrated Approach awarded by University of Colorado - Boulder (Principal Investigator). 2014 to 2015

Subcontract - Social Demographic Moderation of Genome Wide Associations for Body Mass Index awarded by University of Colorado - Boulder (Principal Investigator). 2014 to 2015