Roberto Cabeza

Roberto Cabeza

Professor of Psychology and Neuroscience

Education & Training

  • Ph.D., University of Tsukuba (Japan) 1994

Overview

My laboratory investigates the neural correlates of memory and cognition in young and older adults using fMRI. We have three main lines of research: First, we distinguish the neural correlates of various episodic memory processes. For example, we have compared encoding vs. retrieval, item vs. source memory, recall vs. recognition, true vs. false memory, and emotional vs. nonemotional memory. We are particularly interested in the contribution of prefrontal cortex (PFC) and medial temporal lobe (MTL) subregions and their interactions.Second, we investigate similarities and differences between the neural correlates of episodic memory and other memory and cognitive functions (working, semantic, implicit, and procedural memory; attention; perception, etc.). The main goal of this cross-functional approach is to understand the contributions of brain regions shared by different cognitive functions. Finally, in both episodic memory and cross-function studies, we also examine the effects of healthy and pathological aging. Regarding episodic memory, we have linked processes differentially affected by aging (e.g., item vs. source memory, recall vs. recognition) to the effects of aging on specific PFC and MTL subregions. Regarding cross-function comparisons, we identify age-related changes in activity that are common to various functions. For example, we have found an age-related increase in bilaterality that occurs for many functions (memory, attention, language, perception, and motor) and is associated with functional compensation.

Expertise

Episodic memory, semantic memory, visual memory, attention effects on memory, healthy aging, Alzheimer's Disease, fMRI, TMS, cognitive neuroscience

Cabeza, R, Stanley, ML, and Moscovitch, M. "Process-Specific Alliances (PSAs) in Cognitive Neuroscience." Trends in Cognitive Sciences (September 14, 2018). (Review) Full Text

Wang, W-C, Wing, EA, Murphy, DLK, Luber, BM, Lisanby, SH, Cabeza, R, and Davis, SW. "Excitatory TMS modulates memory representations." Cognitive Neuroscience (September 5, 2018): 1-16. Full Text

Monge, ZA, Stanley, ML, Geib, BR, Davis, SW, and Cabeza, R. "Functional networks underlying item and source memory: shared and distinct network components and age-related differences." Neurobiology of Aging 69 (September 2018): 140-150. Full Text

Lighthall, NR, Pearson, JM, Huettel, SA, and Cabeza, R. "Feedback-Based Learning in Aging: Contributions and Trajectories of Change in Striatal and Hippocampal Systems." The Journal of Neuroscience : the Official Journal of the Society for Neuroscience 38.39 (September 2018): 8453-8462. Full Text

Martinikorena, I, Cabeza, R, Villanueva, A, Urtasun, I, and Larumbe, A. "Fast and robust ellipse detection algorithm for head-mounted eye tracking systems." Machine Vision and Applications 29.5 (July 2018): 845-860. Full Text

Wang, W-C, Brashier, NM, Wing, EA, Marsh, EJ, and Cabeza, R. "Knowledge supports memory retrieval through familiarity, not recollection." Neuropsychologia 113 (May 2018): 14-21. Full Text

Wing, EA, Iyengar, V, Hess, TM, LaBar, KS, Huettel, SA, and Cabeza, R. "Neural mechanisms underlying subsequent memory for personal beliefs:An fMRI study." Cognitive, affective & behavioral neuroscience 18.2 (April 2018): 216-231. Full Text

Monge, ZA, Wing, EA, Stokes, J, and Cabeza, R. "Search and recovery of autobiographical and laboratory memories: Shared and distinct neural components." Neuropsychologia 110 (February 2018): 44-54. Full Text

Browndyke, JN, Berger, M, Smith, PJ, Harshbarger, TB, Monge, ZA, Panchal, V, Bisanar, TL, Glower, DD, Alexander, JH, Cabeza, R, Welsh-Bohmer, K, Newman, MF, Mathew, JP, and Duke Neurologic Outcomes Research Group (NORG), . "Task-related changes in degree centrality and local coherence of the posterior cingulate cortex after major cardiac surgery in older adults." Human Brain Mapping 39.2 (February 2018): 985-1003. Full Text Open Access Copy

Fandakova, Y, Sander, MC, Grandy, TH, Cabeza, R, Werkle-Bergner, M, and Shing, YL. "Age differences in false memory: The importance of retrieval monitoring processes and their modulation by memory quality." Psychology and Aging 33.1 (February 2018): 119-133. Full Text

Pages

Doshi, A, Cabeza, R, and Berger, M. "Geriatric anesthesia: Age-dependent changes in the central and peripheral nervous systems." Geriatric Anesthesiology: Third Edition. October 27, 2017. 145-160. Full Text

Jacques, PL, and Cabeza, R. "Neural Basis of Autobiographical Memory." Origins and Development of Recollection: Perspectives from Psychology and Neuroscience. May 24, 2012. Full Text

Cabeza, R. "Prefrontal and medial temporal lobe contributions to relational memory in young and older adults." Handbook of Binding and Memory: Perspectives from Cognitive Neuroscience. March 22, 2012. Full Text

Villanueva, A, Cabeza, R, and Agustin, JS. "Gaze estimation." Gaze Interaction and Applications of Eye Tracking: Advances in Assistive Technologies. December 1, 2011. 310-325. Full Text

Daselaar, S, and Cabeza, R. "Age-related changes in hemispheric organization." Cognitive Neuroscience of Aging: Linking cognitive and cerebral aging. May 1, 2009. Full Text

Cabeza, R, Nyberg, L, and Park, DC. "Cognitive Neuroscience of Aging: Emergence of a New Discipline." Cognitive Neuroscience of Aging: Linking cognitive and cerebral aging. May 1, 2009. Full Text

Dolcos, F, LaBar, KS, and Cabeza, R. "The Memory Enhancing Effect of Emotion: Functional Neuroimaging Evidence." Memory and Emotion: Interdisciplinary Perspectives. January 11, 2008. 105-134. Full Text

Cabeza, R, Purves, D, Huettel, SA, LaBar, KS, Platt, ML, and Woldorff, MG. Principles of Cognitive Neuroscience. Sinauer Associates Incorporated, 2012.

Cabeza, R, and Kingstone, A. Handbook of Functional Neuroimaging of Congnition. 2006.

Martinikorena, I, Villanueva, A, Cabeza, R, and Porta, S. "Introducing I2head database." June 15, 2018. Full Text

Larumbe, A, Ariz, M, Bengoechea, JJ, Segura, R, Cabeza, R, and Villanueva, A. "Improved Strategies for HPE Employing Learning-by-Synthesis Approaches." January 19, 2018. Full Text

Beynel, L, Davis, SW, Crowell, C, Hilbig, SA, Lim, W, Nguyen, D, Peterchev, AV, Lisanby, SH, Cabeza, R, Appelbaum, G, and Luber, B. "fMRI- and Computationally-Guided rTMS Enhances Performance in Working Memory Manipulation." November 2017.

Cerrolaza, JJ, Villanueva, A, Reyes, M, Cabeza, R, González Ballester, MA, and Linguraru, MG. "Generalized multiresolution hierarchical shape models via automatic landmark clusterization." January 1, 2014. Full Text

Sesma-Sanchez, L, Villanueva, A, and Cabeza, R. "Design issues of remote eye tracking systems with large range of movement." January 1, 2014. Full Text

Cerrolaza, JJ, Herrezuelo, NC, Villanueva, A, Cabeza, R, González Ballester, MA, and Linguraru, MG. "Multiresolution hierarchical shape models in 3D subcortical brain structures." October 24, 2013. Full Text

Madden, D, Davis, S, and Cabeza, R. "AGE-RELATED DIFFERENCES IN THE FUNCTIONAL NEUROANATOMY OF TOP-DOWN ATTENTIONAL CONTROL DURING VISUAL SEARCH." 20th Annual Meeting of the Cognitive-Neuroscience-Society. April 13, 2013 - April 16, 2013. San Francisco, CA.: MIT PRESS, January 1, 2013.

Brashier, N, Dew, I, Ritchey, M, LaBar, K, and Cabeza, R. "PERCEPTUAL PROCESSING ENHANCES THE EFFECT OF EMOTION ON RETRIEVAL: AN FMRI STUDY." 20th Annual Meeting of the Cognitive-Neuroscience-Society. April 13, 2013 - April 16, 2013. San Francisco, CA.: MIT PRESS, January 1, 2013.

Brooks, J, Davis, S, Komes, J, and Cabeza, R. "NEURAL CORRELATES OF THE OWN-AGE BIAS IN YOUNGER AND OLDER ADULTS." 20th Annual Meeting of the Cognitive-Neuroscience-Society. April 13, 2013 - April 16, 2013. San Francisco, CA.: MIT PRESS, January 1, 2013.

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Selected Grants

Effects of Aging on Episodic Memory-Dependent Decision Making awarded by National Institutes of Health (Principal Investigator). 2018 to 2023

Neuro-inflammation in Postoperative Cognitive Dysfunction: CSF and fMRI Studies awarded by National Institutes of Health (Advisor). 2017 to 2022

Impact of Timing, Targeting, and Brain State on rTMS of Human and Non-Human Primates awarded by National Institutes of Health (Co Investigator). 2017 to 2021

Behavioral and Physiology in Aging awarded by National Institutes of Health (Mentor). 2015 to 2020

Memory Representations in Aging awarded by National Institutes of Health (Principal Investigator). 2018 to 2020

Training Autobiographical Memory Retrieval in Healthy Older Adults Using Novel Lifelogging Technology awarded by National Institutes of Health (Principal Investigator). 2018 to 2020

Using fMRI-guided TMS to increase central executive function in older adults awarded by National Institutes of Health (Co-Principal Investigator). 2015 to 2020

Spatiotemporal Dynamics of Memory Reactivation awarded by National Institutes of Health (Co-Sponsor). 2018 to 2019

Effects of Aging on Visual Memory: Neuroimaging Studies awarded by National Institutes of Health (Principal Investigator). 2001 to 2018

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