The electrophysiology of excitable cells from a quantitative perspective. Topics include ionic basis of action potentials, Hodgkin-Huxley model, impulse propagation, extracellular measurements, and introduction to functional electrical stimulation. Labs include stimulation and recording of nerve and heart potentials, optical imaging of excitation waves, and numerical modeling. In a final project, students design and perform their own experiments based on the classical literature and the skills they learned in the course. Not open to students who have taken BME 301L or equivalent. Prerequisites: recommended a circuits course and knowledge of ordinary and partial differential equations.