Ahmad Hariri

Ahmad Hariri

Professor of Psychology and Neuroscience

Education & Training

  • Ph.D., University of California at Los Angeles 2000

  • M.S., University of Maryland, College Park 1997

  • B.S., University of Maryland, College Park 1994

Overview

Integrating psychology, neuroimaging, pharmacology and molecular genetics in the search for biological pathways mediating individual differences in behavior and related risk for psychopathology.

Expertise

Neuroscience, genetics, psychopathology risk, individual differences

Lam, M, Trampush, JW, Yu, J, Knowles, E, Djurovic, S, Melle, I, Sundet, K, Christoforou, A, Reinvang, I, DeRosse, P, Lundervold, AJ, Steen, VM, Espeseth, T, Räikkönen, K, Widen, E, Palotie, A, Eriksson, JG, Giegling, I, Konte, B, Roussos, P, Giakoumaki, S, Burdick, KE, Payton, A, Ollier, W, Chiba-Falek, O, Attix, DK, Need, AC, Cirulli, ET, Voineskos, AN, Stefanis, NC, Avramopoulos, D, Hatzimanolis, A, Arking, DE, Smyrnis, N, Bilder, RM, Freimer, NA, Cannon, TD, London, E, Poldrack, RA, Sabb, FW, Congdon, E, Conley, ED, Scult, MA, Dickinson, D, Straub, RE, Donohoe, G, Morris, D, Corvin, A, Gill, M, Hariri, AR, Weinberger, DR, Pendleton, N, Bitsios, P, Rujescu, D, Lahti, J, Hellard, SL, Keller, MC, Andreassen, OA, Glahn, DC, Malhotra, AK, and Lencz, T. "Multi-Trait Analysis of GWAS and Biological Insights Into Cognition: A Response to Hill (2018)." Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies 21.5 (October 2018): 394-397. Full Text

d'Arbeloff, TC, Kim, MJ, Knodt, AR, Radtke, SR, Brigidi, BD, and Hariri, AR. "Microstructural integrity of a pathway connecting the prefrontal cortex and amygdala moderates the association between cognitive reappraisal and negative emotions." Emotion (Washington, D.C.) 18.6 (September 2018): 912-915. Full Text

Avinun, R, Nevo, A, Knodt, AR, Elliott, ML, and Hariri, AR. "Replication in Imaging Genetics: The Case of Threat-Related Amygdala Reactivity." Biological Psychiatry 84.2 (July 2018): 148-159. Full Text

Kim, MJ, Scult, MA, Knodt, AR, Radtke, SR, d'Arbeloff, TC, Brigidi, BD, and Hariri, AR. "A Link Between Childhood Adversity and Trait Anger Reflects Relative Activity of the Amygdala and Dorsolateral Prefrontal Cortex." Biological Psychiatry. Cognitive Neuroscience and Neuroimaging 3.7 (July 2018): 644-649. Full Text

Savage, JE, Jansen, PR, Stringer, S, Watanabe, K, Bryois, J, de Leeuw, CA, Nagel, M, Awasthi, S, Barr, PB, Coleman, JRI, Grasby, KL, Hammerschlag, AR, Kaminski, JA, Karlsson, R, Krapohl, E, Lam, M, Nygaard, M, Reynolds, CA, Trampush, JW, Young, H, Zabaneh, D, Hägg, S, Hansell, NK, Karlsson, IK, Linnarsson, S, Montgomery, GW, Muñoz-Manchado, AB, Quinlan, EB, Schumann, G, Skene, NG, Webb, BT, White, T, Arking, DE, Avramopoulos, D, Bilder, RM, Bitsios, P, Burdick, KE, Cannon, TD, Chiba-Falek, O, Christoforou, A, Cirulli, ET, Congdon, E, Corvin, A, Davies, G, Deary, IJ, DeRosse, P, Dickinson, D, Djurovic, S, Donohoe, G, Conley, ED, Eriksson, JG, Espeseth, T, Freimer, NA, Giakoumaki, S, Giegling, I, Gill, M, Glahn, DC, Hariri, AR, Hatzimanolis, A, Keller, MC, Knowles, E, Koltai, D, Konte, B, Lahti, J, Le Hellard, S, Lencz, T, Liewald, DC, London, E, Lundervold, AJ, Malhotra, AK, Melle, I, Morris, D, Need, AC, Ollier, W, Palotie, A, Payton, A, Pendleton, N, Poldrack, RA, Räikkönen, K, Reinvang, I, Roussos, P, Rujescu, D, Sabb, FW, Scult, MA, Smeland, OB, Smyrnis, N, Starr, JM, Steen, VM, Stefanis, NC, Straub, RE, Sundet, K, Tiemeier, H, Voineskos, AN, Weinberger, DR, Widen, E, Yu, J, Abecasis, G, Andreassen, OA, Breen, G, Christiansen, L, Debrabant, B, Dick, DM, Heinz, A, Hjerling-Leffler, J, Ikram, MA, Kendler, KS, Martin, NG, Medland, SE, Pedersen, NL, Plomin, R, Polderman, TJC, Ripke, S, van der Sluis, S, Sullivan, PF, Vrieze, SI, Wright, MJ, and Posthuma, D. "Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence." Nature Genetics 50.7 (July 2018): 912-919. Full Text

Miller, JA, Scult, MA, Conley, ED, Chen, Q, Weinberger, DR, and Hariri, AR. "Effects of Schizophrenia Polygenic Risk Scores on Brain Activity and Performance During Working Memory Subprocesses in Healthy Young Adults." Schizophrenia Bulletin 44.4 (June 2018): 844-853. Full Text

Davies, G, Lam, M, Harris, SE, Trampush, JW, Luciano, M, Hill, WD, Hagenaars, SP, Ritchie, SJ, Marioni, RE, Fawns-Ritchie, C, Liewald, DCM, Okely, JA, Ahola-Olli, AV, Barnes, CLK, Bertram, L, Bis, JC, Burdick, KE, Christoforou, A, DeRosse, P, Djurovic, S, Espeseth, T, Giakoumaki, S, Giddaluru, S, Gustavson, DE, Hayward, C, Hofer, E, Ikram, MA, Karlsson, R, Knowles, E, Lahti, J, Leber, M, Li, S, Mather, KA, Melle, I, Morris, D, Oldmeadow, C, Palviainen, T, Payton, A, Pazoki, R, Petrovic, K, Reynolds, CA, Sargurupremraj, M, Scholz, M, Smith, JA, Smith, AV, Terzikhan, N, Thalamuthu, A, Trompet, S, van der Lee, SJ, Ware, EB, Windham, BG, Wright, MJ, Yang, J, Yu, J, Ames, D, Amin, N, Amouyel, P, Andreassen, OA, Armstrong, NJ, Assareh, AA, Attia, JR, Attix, D, Avramopoulos, D, Bennett, DA, Böhmer, AC, Boyle, PA, Brodaty, H, Campbell, H, Cannon, TD, Cirulli, ET, Congdon, E, Conley, ED, Corley, J, Cox, SR, Dale, AM, Dehghan, A, Dick, D, Dickinson, D, Eriksson, JG, Evangelou, E, Faul, JD, Ford, I, Freimer, NA, Gao, H, Giegling, I, Gillespie, NA, Gordon, SD, Gottesman, RF, Griswold, ME, Gudnason, V, Harris, TB, Hartmann, AM, Hatzimanolis, A, Heiss, G, Holliday, EG, Joshi, PK, Kähönen, M, Kardia, SLR, Karlsson, I, Kleineidam, L, Knopman, DS, Kochan, NA, Konte, B, Kwok, JB, Le Hellard, S, Lee, T, Lehtimäki, T, Li, S-C, Liu, T, Koini, M, London, E, Longstreth, WT, Lopez, OL, Loukola, A, Luck, T, Lundervold, AJ, Lundquist, A, Lyytikäinen, L-P, Martin, NG, Montgomery, GW, Murray, AD, Need, AC, Noordam, R, Nyberg, L, Ollier, W, Papenberg, G, Pattie, A, Polasek, O, Poldrack, RA, Psaty, BM, Reppermund, S, Riedel-Heller, SG, Rose, RJ, Rotter, JI, Roussos, P, Rovio, SP, Saba, Y, Sabb, FW, Sachdev, PS, Satizabal, CL, Schmid, M, Scott, RJ, Scult, MA, Simino, J, Slagboom, PE, Smyrnis, N, Soumaré, A, Stefanis, NC, Stott, DJ, Straub, RE, Sundet, K, Taylor, AM, Taylor, KD, Tzoulaki, I, Tzourio, C, Uitterlinden, A, Vitart, V, Voineskos, AN, Kaprio, J, Wagner, M, Wagner, H, Weinhold, L, Wen, KH, Widen, E, Yang, Q, Zhao, W, Adams, HHH, Arking, DE, Bilder, RM, Bitsios, P, Boerwinkle, E, Chiba-Falek, O, Corvin, A, De Jager, PL, Debette, S, Donohoe, G, Elliott, P, Fitzpatrick, AL, Gill, M, Glahn, DC, Hägg, S, Hansell, NK, Hariri, AR, Ikram, MK, Jukema, JW, Vuoksimaa, E, Keller, MC, Kremen, WS, Launer, L, Lindenberger, U, Palotie, A, Pedersen, NL, Pendleton, N, Porteous, DJ, Räikkönen, K, Raitakari, OT, Ramirez, A, Reinvang, I, Rudan, I, Dan Rujescu, , Schmidt, R, Schmidt, H, Schofield, PW, Schofield, PR, Starr, JM, Steen, VM, Trollor, JN, Turner, ST, Van Duijn, CM, Villringer, A, Weinberger, DR, Weir, DR, Wilson, JF, Malhotra, A, McIntosh, AM, Gale, CR, Seshadri, S, Mosley, TH, Bressler, J, Lencz, T, and Deary, IJ. "Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function." Nature Communications 9.1 (May 29, 2018): 2098-null. Full Text

Agrawal, A, Chou, Y-L, Carey, CE, Baranger, DAA, Zhang, B, Sherva, R, Wetherill, L, Kapoor, M, Wang, J-C, Bertelsen, S, Anokhin, AP, Hesselbrock, V, Kramer, J, Lynskey, MT, Meyers, JL, Nurnberger, JI, Rice, JP, Tischfield, J, Bierut, LJ, Degenhardt, L, Farrer, LA, Gelernter, J, Hariri, AR, Heath, AC, Kranzler, HR, Madden, PAF, Martin, NG, Montgomery, GW, Porjesz, B, Wang, T, Whitfield, JB, Edenberg, HJ, Foroud, T, Goate, AM, Bogdan, R, and Nelson, EC. "Genome-wide association study identifies a novel locus for cannabis dependence." Molecular Psychiatry 23.5 (May 2018): 1293-1302. Full Text

Chen, Q, Ursini, G, Romer, AL, Knodt, AR, Mezeivtch, K, Xiao, E, Pergola, G, Blasi, G, Straub, RE, Callicott, JH, Berman, KF, Hariri, AR, Bertolino, A, Mattay, VS, and Weinberger, DR. "Schizophrenia polygenic risk score predicts mnemonic hippocampal activity." Brain 141.4 (April 1, 2018): 1218-1228. Full Text

Romer, AL, Knodt, AR, Houts, R, Brigidi, BD, Moffitt, TE, Caspi, A, and Hariri, AR. "Structural alterations within cerebellar circuitry are associated with general liability for common mental disorders." Molecular Psychiatry 23.4 (April 2018): 1084-1090. Full Text

Pages

Faig, KE, Nikolova, YS, and Hariri, AR. "Genetic Neuroimaging of Social Perception." Brain Mapping: An Encyclopedic Reference. February 14, 2015. 97-105. Full Text

Selected Grants

Evaluating neurodegenerative risk in middle-aged adults exposed to lead as children awarded by National Institutes of Health (Co-Principal Investigator). 2018 to 2021

Neural signatures of healthy and unhealthy aging awarded by National Institutes of Health (Principal Investigator). 2015 to 2020

A Compute Cluster for Brain Imaging and Analysis awarded by National Institutes of Health (Major User). 2016 to 2017

Neurogenetic Pathways to Drug Use in Young Adults awarded by National Institutes of Health (Principal Investigator). 2013 to 2017

Instructed Activation of the Human Dopaminergic Midbrain using Real-Time fMRI awarded by National Institutes of Health (Co-Sponsor). 2014 to 2016

Self-Regulation Failure: Identifying and Modifying a Risk Phenotype awarded by National Institutes of Health (Co-Principal Investigator). 2010 to 2014

From Phenotype to Mechanism: Mapping the Pathways underlying Risky Choice awarded by National Institutes of Health (Co Investigator). 2009 to 2011

Development of Amygdala-Prefrontal Interactions awarded by National Institute of Mental Health (Principal Investigator). 2005 to 2010