Professor of Psychology and Neuroscience and Director of Graduate Studies
Education & Training
Ph.D., University of California - Los Angeles 2004
I am interested in understanding the neural mechanisms underlying goal-directed actions. For the first time in history, advances in psychology and neurobiology have made it feasible to pursue the detailed neural mechanisms underlying goal-directed and voluntary actions--how they are driven by the needs and desires of the organism and controlled by cognitive processes that provide a rich representation of the self and the world. My approach to this problem is highly integrative, combining behavioral analysis with electrophysiological techniques as well as tools from molecular biology. In the near future three techniques will be emphasized. 1) Dissecting reward-guided behavior using analytical behavioral assays. 2) In vivo recording from cerebral cortex, thalamus, midbrain, and basal ganglia in awake behaving rodents. Up to hundreds of neurons can be recorded from multiple brain areas that form a functional neural network in a single animal. 3) In vitro (and ex vivo) whole-cell patch-clamp recording in brain slices, with the aid of genetic tools for visualization of distinct neuronal populations. Ultimately, I hope to characterize goal-directed actions at multiple levels of analysis--from molecules to neural networks. This knowledge will provide us with insight into various pathological conditions characterized by impaired goal-directed behaviors, such as drug addiction, obsessive-compulsive disorder, Parkinson's disease, and Huntington's disease.
Reward, action, goal, learning, habit, basal ganglia, brain, motivation
Yin, H. H., et al. “Lesions of the dorsolateral striatum abolish habits and preserve goal expectancy.” European Journal of Neuroscience, vol. 19, 2004, pp. 1–9.
Yin, Henry, et al. “Kainic acid lesions disrupt fear-mediated memory processing.” Neurobiology of Learning and Memory, vol. 77, no. 3, May 2002, pp. 389–401. Epmc, doi:10.1006/nlme.2001.4037. Full Text
Yin, H. H., and B. J. Knowlton. “Reinforcer devaluation abolishes conditioned cue preference: evidence for stimulus-stimulus associations.” Behavioral Neuroscience, vol. 116, no. 1, Feb. 2002, pp. 174–77. Epmc, doi:10.1037//0735-7044.116.1.174. Full Text
Kwong-yin Fock, H. “Retail outlet location decision maker – franchisor or franchisee?” Marketing Intelligence &Amp; Planning, vol. 19, no. 3, June 2001, pp. 171–79. Scopus, doi:10.1108/02634500110391717. Full Text